Semax
Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4-10). In preclinical research it is studied for its interaction with BDNF/NGF-related neurotrophic signaling pathways in model systems. Supplied lyophilized for in vitro research. For research use only — not for human or veterinary consumption, diagnosis, or treatment. This compound has not been evaluated by the FDA.
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Molecular Weight | 813.93 g/mol |
| Molecular Formula | C37H51N9O10S |
| CAS Number | 80714-61-4 |
| Target / Receptor | BDNF/trkB pathway; ACTH fragment analog |
| Physical Form | Lyophilized Powder |
| Storage | -20°C, protect from light |
Reconstitution Guide
For laboratory research use only. Follow aseptic technique throughout.
Equilibrate Temperature
Remove the vial from the freezer and allow it to reach room temperature before opening. This prevents condensation from entering the vial.
Wait 15–20 minutes at room temperature
Add Bacteriostatic Water
Reconstitute in sterile saline or bacteriostatic water. Stable for up to 3 weeks at 4°C after reconstitution.
Use a sterile graduated syringe or pipette for precise measurement
Dissolve Gently
Gently swirl or roll the vial between your palms until the peptide is fully dissolved. Do not shake vigorously or vortex — this can cause aggregation and degrade the compound.
Solution should appear clear to slightly opalescent
Aliquot & Store
Transfer reconstituted solution into sterile single-use vials to avoid repeated septum punctures. Store working aliquots at 4°C (use within 28 days) or freeze at -20°C for long-term storage.
Avoid more than 3 freeze-thaw cycles
Concentration Reference (per 1 mg peptide)
| Bacteriostatic Water | Concentration | In µg/mL |
|---|---|---|
| 1 mL | 1 mg/mL | 1,000 mcg/mL |
| 2 mL | 0.5 mg/mL | 500 mcg/mL |
| 5 mL | 0.2 mg/mL | 200 mcg/mL |
| 10 mL | 0.1 mg/mL | 100 mcg/mL |
Storage Conditions
-20°C, protect from light
